Document Details

Document Type : Article In Journal 
Document Title :
Hepatitis C Virus Infection in Pregnant Women and its Vertical Transmission in Jeddah, Saudi Arabia
عدوى الالتهاب الكبدي الفيروسي ج في الحوامل وانتقاله الرأسي بجدة بالمملكة العربية السعودية
 
Subject : Original Articles 
Document Language : English 
Abstract : The aim of this study was to evaluate the prevalence of Hepatitis C virus (HCV) infection among pregnant women and the possibility of its transmission through the vertical route and through breast-feeding. Blood samples were collected from 300 pregnant women at the perinatal period and at delivery from the cord blood of their newborns, and from other 300 randomly selected breast-fed infants. Serum transaminases, anti-HCV Ab and HCV-RNA by PCR for only those with positive anti- HCV Ab were investigated. Results revealed that 9 (3%) mothers were positive for anti-HCV Ab and 8 (2.7%) were positive for HCV-RNA (viral load was below 5,000 copies / ml). However, only 5 newborns of HCV-RNA positive mothers showed positive results in (1.6%) for anti- HCV Ab, while all of them were negative by HCV-RNA. Meanwhile, all of the breast-fed infants were negative for anti- HCV Ab. Thus, this study could not reveal HCV transmission from mother to infant during the period of observation, yet a vertical transmission of HCV Ab was noticed. It is felt that it is not necessary to advise against breast-feeding prevention by mothers with HCV infection as long as there is no nipple cracking or bleeding. 
ISSN : 1319-1004 
Journal Name : Medical Science Journal 
Volume : 14 
Issue Number : 1 
Publishing Year : 1428 AH
2007 AD 
Number Of Pages : 8 
Article Type : Article 
Added Date : Sunday, October 11, 2009 

Researchers

Researcher Name (Arabic)Researcher Name (English)Researcher TypeDr GradeEmail
عبدالله أحمد الغامديAbdullah A. Al-GhamdiResearcher  

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